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Population-Based Precision Cancer Screening: A Symposium on Evidence, Epidemiology, and Next Steps

Marcus, PM; Pashayan, N; Church, TR; Doria-Rose, VP; Gould, MK; Hubbard, RA; Marrone, M; ... Khoury, MJ; + view all (2016) Population-Based Precision Cancer Screening: A Symposium on Evidence, Epidemiology, and Next Steps. Cancer Epidemiology, Biomarkers & Prevention , 25 (11) pp. 1449-1455. 10.1158/1055-9965.EPI-16-0555. Green open access

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Abstract

Precision medicine, an emerging approach for disease treatment that takes into account individual variability in genes, environment, and lifestyle, is under consideration for preventive interventions, including cancer screening. On September 29, 2015, the National Cancer Institute sponsored a symposium entitled “Precision Cancer Screening in the General Population: Evidence, Epidemiology, and Next Steps”. The goal was two-fold: to share current information on the evidence, practices, and challenges surrounding precision screening for breast, cervical, colorectal, lung, and prostate cancers, and to allow for in-depth discussion among experts in relevant fields regarding how epidemiology and other population sciences can be used to generate evidence to inform precision screening strategies. Attendees concluded that the strength of evidence for efficacy and effectiveness of precision strategies varies by cancer site, that no one research strategy or methodology would be able or appropriate to address the many knowledge gaps in precision screening, and that issues surrounding implementation must be researched as well. Additional discussion needs to occur to identify the high priority research areas in precision cancer screening for pertinent organs and to gather the necessary evidence to determine whether further implementation of precision cancer screening strategies in the general population would be feasible and beneficial.

Type: Article
Title: Population-Based Precision Cancer Screening: A Symposium on Evidence, Epidemiology, and Next Steps
Open access status: An open access version is available from UCL Discovery
DOI: 10.1158/1055-9965.EPI-16-0555
Publisher version: http://doi.org/10.1158/1055-9965.EPI-16-0555
Language: English
Additional information: © 2016 American Association for Cancer Research.
Keywords: Science & Technology, Life Sciences & Biomedicine, Oncology, Public, Environmental & Occupational Health, PROSTATE-CANCER, COLORECTAL-CANCER, LUNG-CANCER, SUSCEPTIBILITY LOCI, CERVICAL-CANCER, BREAST-CANCER, HUMAN-PAPILLOMAVIRUS, COST-EFFECTIVENESS, UNITED-STATES, TASK-FORCE
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Applied Health Research
URI: https://discovery.ucl.ac.uk/id/eprint/1508103
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