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New biocompatible hydroxy double salts and their drug delivery properties

Kaassis, AYA; Wei, M; Williams, GR; (2016) New biocompatible hydroxy double salts and their drug delivery properties. Journal Of Materials Chemistry B , 4 (35) pp. 5789-5793. 10.1039/c6tb01108j. Green open access

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Abstract

Two biocompatible hydroxy double salts (HDSs) were synthesised for the first time and loaded with active pharmaceutical ingredients. Drug release was studied from these intercalates, and sustained release observed. The HDS–drug composites were further formulated into tablets which were found to comply with pharmacopeia requirements for delayed and extended release dosage forms.

Type: Article
Title: New biocompatible hydroxy double salts and their drug delivery properties
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c6tb01108j
Publisher version: http://doi.org/10.1039/c6tb01108j
Language: English
Additional information: Copyright © The Royal Society of Chemistry 2017. All rights reserved.
Keywords: Science & Technology, Technology, Materials Science, Biomaterials, Materials Science, Layered Double Hydroxides, Controlled-release, Thermal-decomposition, Intercalation, Zinc, Oxyanions, Naproxen, Removal, Ability, System
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/1508088
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