Macerollo, A;
Martino, D;
(2016)
What is new in Tics, Dystonia and Chorea?
Clinical Medicine
, 16
(4)
pp. 383-389.
10.7861/clinmedicine.16-4-383.
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Abstract
Movement disorders comprise hyperkinetic involuntary movements (eg tremor, myoclonus, tics, dystonia and chorea) and hypokinetic (parkinsonism) disorders. Tics are cardinal features of primary tic disorders encompassing Tourette syndrome (TS), but are also found in some neurodegenerative conditions and may be induced by psychoactive substances. The first line treatment for tics is pharmacological (mainly dopamine receptor blockers or alpha-2 adrenergic agonists) and behavioural. Dystonia and chorea syndromes are considerably heterogeneous in aetiology, and age at onset, body distribution of the movement disorder, accompanying neurological motor and non-motor features, and systemic manifestations are all important to reach a correct aetiological diagnosis. While symptomatic pharmacological treatment remains the mainstay of treatment for choreas, deep brain stimulation surgery has a well-defined place in the management of medically refractory dystonia.
| Type: | Article |
|---|---|
| Title: | What is new in Tics, Dystonia and Chorea? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.7861/clinmedicine.16-4-383 |
| Publisher version: | http://dx.doi.org/10.7861/clinmedicine.16-4-383 |
| Language: | English |
| Additional information: | © Royal College of Physicians 2016. All rights reserved |
| Keywords: | Chorea, diagnosis, dystonia, hyperkinetic movement disorders, tics, treatments. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1507884 |
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