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Intra-Operative Assessment of Sentinel Lymph Nodes in Breast Cancer

Banerjee, SM; El-Sheikh, S; Keshtgar, MRS; (2014) Intra-Operative Assessment of Sentinel Lymph Nodes in Breast Cancer. Archives of Breast Cancer , 1 (2) pp. 44-52. 10.19187/abc.20141244-52. Green open access

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Abstract

Lymph node status remains an important prognostic indicator for survival in breast cancer. Sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. Economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. Review of the emerging trends in the last 4 years show that although routine histological examination remains the gold standard in most centres intra-operative assessment remains the most favourable, timely and cost-effective option to analyse sentinel nodes. Molecular techniques appear to be far more superior to other histological tests such as Frozen Section or Touch Imprint Cytology. Emerging research suggests that molecular techniques can be used to predict the presence of non sentinel node metastasis.

Type: Article
Title: Intra-Operative Assessment of Sentinel Lymph Nodes in Breast Cancer
Open access status: An open access version is available from UCL Discovery
DOI: 10.19187/abc.20141244-52
Publisher version: http://dx.doi.org/10.19187/abc.20141244-52
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Keywords: Frozen Section; Intraoperative Care; Sentinel Lymph Node
URI: https://discovery.ucl.ac.uk/id/eprint/1507867
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