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Opportunities for phase-based computed tomography in the laboratory

Hagen, CK; Zamir, A; Diemoz, PC; Endrizzi, M; Vittoria, FA; Maghsoudlou, P; Coan, P; ... Olivo, A; + view all (2016) Opportunities for phase-based computed tomography in the laboratory. In: Kachelriess, M, (ed.) CT- Meeting 2016: Proceedings of the 4th International Meeting on Image Formation in X-Ray Computed Tomography, 18 - 22 July 2016, Bamberg, Germany. (pp. pp. 363-366). ct-meeting.org Green open access

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Abstract

It has been demonstrated in many instances that phase-based computed tomography (CT) can provide superior contrast-to-noise ratio for weakly attenuating samples than attenuation-based CT. In order to exploit this benefit on a wider scale, phase-based tomography implementations must be compatible with standard x-ray equipment. The edge illumination method, which is based on aperturing a beam and measuring spatial displacements caused by refraction, is an attractive choice for such use due to its low requirements on spatial and temporal coherence. This document provides a brief introduction to the working principle of the edge illumination method and reviews recent advances that lead to increased robustness, faster acquisitions and lower dose delivery. Moreover, it reports on a recent study in which the edge illumination method was applied to samples from the field of tissue engineering, yielding synchrotron-like image quality with exclusively commercially available, laboratory-based x-ray equipment.

Type: Proceedings paper
Title: Opportunities for phase-based computed tomography in the laboratory
Event: 4th International Conference on Image Formation in X-Ray Computed Tomography, 18 - 22 July 2016, Bamberg, Germany
Location: Bamberg, Germany
Dates: 18 July 2016 - 22 July 2016
Open access status: An open access version is available from UCL Discovery
Publisher version: http://ct-meeting.org/data/ProceedingsCTMeeting201...
Language: English
Additional information: Copyright © The copyright for any material created by the author is reserved. Any duplication or use of objects such as diagrams, sounds or texts in other electronic or printed publications is not permitted without the author's agreement.
Keywords: computed tomography, phase contrast imaging, x-ray imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1505713
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