Gourine, AV;
Machhada, A;
Trapp, S;
Spyer, KM;
(2016)
Cardiac vagal preganglionic neurones: An update.
Autonomic Neuroscience
, 199
pp. 24-28.
10.1016/j.autneu.2016.06.003.
Preview |
Text (Accepted manuscript)
Gourine_Cardiac vagal preganglionic neurones_AAM.pdf - Accepted Version Download (151kB) | Preview |
Preview |
Text (Supplementary figure)
Gourine_Cardiac vagal preganglionic neurones_Fig.pdf - Accepted Version Download (2MB) | Preview |
Abstract
The autonomic nervous system controls the heart by dynamic recruitment and withdrawal of cardiac parasympathetic and sympathetic activities. These activities are generated by groups of sympathoexcitatory and vagal preganglionic neurones residing in a close proximity to each other within well-defined structures of the brainstem. This short essay provides a general overview and an update on the latest developments in our understanding of the central nervous origins and functional significance of cardiac vagal tone. Significant experimental evidence suggests that distinct groups of cardiac vagal preganglionic neurones with different patterns of activity control nodal tissue (controlling the heart rate and atrioventricular conductance) and the ventricular myocardium (modulating its contractility and excitability).
Archive Staff Only
 |
View Item |
