Carter, T;
Mulholland, P;
Chester, K;
(2016)
Antibody-targeted nanoparticles for cancer treatment.
Immunotherapy
, 8
(8)
pp. 941-958.
10.2217/imt.16.11.
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Abstract
Nanoparticles (NPs) are diverse and versatile with physical properties that can be employed for use in cancer medicine. Targeting NPs using antibodies and antibody fragments could overcome some of the limitations seen with current targeted therapies. This review will discuss the role of antibody-targeted NPs in the treatment of cancer: as delivery vehicles, targeted theranostic agents and in the evolving field of cancer hyperthermia.
| Type: | Article |
|---|---|
| Title: | Antibody-targeted nanoparticles for cancer treatment |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.2217/imt.16.11 |
| Publisher version: | http://dx.doi.org/10.2217/imt.16.11 |
| Language: | English |
| Additional information: | Copyright © 2016 Future Medicine Ltd. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Immunology, Antibodies, Cancer Treatment, Clinical Translation, Hyperthermia, Nanoparticles, Targeting, Theranostics, Drug-Delivery Systems, Single-Chain Antibody, Iron-Oxide Nanoparticles, Walled Carbon Nanotubes, Advanced Solid Tumors, Stem-Like Cells, Gold Nanoparticles, Monoclonal-Antibody, Magnetic Nanoparticles, Breast-Cancer |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1504584 |
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