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Autoimmune gastrointestinal complications in patients with Systemic Lupus Erythematosus: case series and literature review

Custódio Alves, S; Fasano, S; Isenberg, DA; (2016) Autoimmune gastrointestinal complications in patients with Systemic Lupus Erythematosus: case series and literature review. Lupus , 25 (14) pp. 1509-1519. 10.1177/0961203316655210. Green open access

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Abstract

The association of systemic lupus erythematosus (SLE) with gastrointestinal autoimmune diseases is rare, but has been described in the literature, mostly as case reports. However, some of these diseases may be very severe, thus a correct and early diagnosis with appropriate management are fundamental. We have analysed our data from the SLE patient cohort at University College Hospital London, established in 1978, identifying those patients with an associated autoimmune gastrointestinal disease. We have also undertaken a review of the literature describing the major autoimmune gastrointestinal pathologies which may be coincident with SLE, focusing on the incidence, clinical and laboratory (particularly antibody) findings, common aetiopathogenesis and complications.

Type: Article
Title: Autoimmune gastrointestinal complications in patients with Systemic Lupus Erythematosus: case series and literature review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/0961203316655210
Publisher version: http://dx.doi.org/10.1177/0961203316655210
Language: English
Additional information: Copyright © The Author(s), 2016.
Keywords: Systemic lupus erythematosus, lupus enteritis, Crohn’s disease, ulcerative colitis, autoimmune hepatic disease, acute pancreatitis, gastrointestinal involvement
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/1502173
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