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Joint segmentation and CT synthesis for MRI-only radiotherapy treatment planning

Burgos, N; Guerreiro, F; McClelland, J; Nill, S; Dearnaley, D; Desouza, N; Oelfke, U; ... Cardoso, MJ; + view all (2016) Joint segmentation and CT synthesis for MRI-only radiotherapy treatment planning. In: Ourselin, S and Joskowicz, L and Sabuncu, M and Unal, G and Wells, W, (eds.) International Conference on Medical Image Computing and Computer-Assisted Intervention. (pp. pp. 547-555). Springer: Cham, Switzerland. Green open access

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Abstract

Accurate knowledge of organ location and tissue attenuation properties are the two essential components to perform radiotherapy treatment planning (RTP). Computed tomography (CT) has been the modality of choice for RTP as it easily provides electron density information. However, its low soft tissue contrast limits the accuracy of organ delineation. On the contrary, magnetic resonance (MR) provides images with excellent soft tissue contrast but its use for RTP is limited by the fact that it does not readily provide tissue attenuation information. In this work we propose a multi-atlas information propagation scheme that jointly segments the organs at risk and generates pseudo CT data from MR images. We demonstrate that the proposed framework is able to automatically generate accurate pseudo CT images and segmentations in the pelvic region, bypassing the need for CT scan for accurate RTP.

Type: Proceedings paper
Title: Joint segmentation and CT synthesis for MRI-only radiotherapy treatment planning
Event: MICCAI 2016: Medical Image Computing and Computer-Assisted Intervention
ISBN-13: 9783319467221
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-3-319-46723-8_63
Publisher version: https://doi.org/10.1007/978-3-319-46723-8_63
Language: English
Additional information: Copyright © Springer International Publishing AG 2016. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-46723-8_63
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1501088
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