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Diffusion-weighted MRI in Crohn's disease: Current status and recommendations

Dohan, A; Taylor, S; Hoeffel, C; Barret, M; Allez, M; Dautry, R; Zappa, M; ... Soyer, P; + view all (2016) Diffusion-weighted MRI in Crohn's disease: Current status and recommendations. Journal of Magnetic Resonance Imaging , 44 (6) pp. 1381-1396. 10.1002/jmri.25325. Green open access

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Abstract

Over the past years, technological improvements and refinements in magnetic resonance imaging (MRI) hardware have made high-quality diffusion-weighted imaging (DWI) routinely possible for the bowel. DWI is promising for the detection and characterization of lesions in Crohn's disease (CD) and has been advocated as an alternative to intravenous gadolinium-based contrast agents. Furthermore, quantification using the apparent diffusion coefficient may have value as a biomarker of CD activity and has shown promise. In this article we critically review the literature pertaining to the value of DWI in CD for detection, characterization, and quantification of disease activity and complications. Although the body of supportive evidence is growing, it is clear that well-designed, multicenter studies are required before the role of DWI in clinical practice can be fully established. J. Magn. Reson. Imaging 2016;44:1381–1396.

Type: Article
Title: Diffusion-weighted MRI in Crohn's disease: Current status and recommendations
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/jmri.25325
Publisher version: http://dx.doi.org/10.1002/jmri.25325
Language: English
Additional information: This is the peer reviewed version of the following article: Dohan, A., Taylor, S., Hoeffel, C., Barret, M., Allez, M., Dautry, R., Zappa, M., Savoye-Collet, C., Dray, X., Boudiaf, M., Reinhold, C. and Soyer, P. (2016), Diffusion-weighted MRI in Crohn's disease: Current status and recommendations. J. Magn. Reson. Imaging, 44: 1381–1396., which has been published in final form at http://dx.doi.org/10.1002/jmri.25325. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: Science & Technology, Life Sciences & Biomedicine, Radiology, Nuclear Medicine & Medical Imaging, Diffusion Weighted Imaging, Crohn's Disease, Mr-Enterography, Mr Imaging, Imaging Techniques, Inflammatory Bowel Disease, Magnetic-Resonance-Enterography, Inflammatory Bowel Diseases, 64-Section CT-Enteroclysis, Fast Spin-Echo, Imaging Findings, B-Value, Percutaneous Drainage, ILEAL Inflammation, Lesion Detection, Follow-Through
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Metabolism and Experi Therapeutics
URI: https://discovery.ucl.ac.uk/id/eprint/1498492
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