Riillo, F;
Bagnato, C;
Allievi, AG;
Takagi, A;
Fabrizi, L;
Saggio, G;
Arichi, T;
(2016)
A Simple fMRI Compatible Robotic Stimulator to Study the Neural Mechanisms of Touch and Pain.
Annals of Biomedical Engineering
, 44
(8)
pp. 2431-2441.
10.1007/s10439-016-1549-y.
Preview |
Text
Riillo et al A Simple fMRI Compatible Robotic Stimulator to Study the Neural Mechanisms of Touch and Pain.pdf Download (1MB) | Preview |
Abstract
This paper presents a simple device for the investigation of the human somatosensory system with functional magnetic imaging (fMRI). PC-controlled pneumatic actuation is employed to produce innocuous or noxious mechanical stimulation of the skin. Stimulation patterns are synchronized with fMRI and other relevant physiological measurements like electroencephalographic activity and vital physiological parameters. The system allows adjustable regulation of stimulation parameters and provides consistent patterns of stimulation. A validation experiment demonstrates that the system safely and reliably identifies clusters of functional activity in brain regions involved in the processing of pain. This new device is inexpensive, portable, easy-to-assemble and customizable to suit different experimental requirements. It provides robust and consistent somatosensory stimulation, which is of crucial importance to investigating the mechanisms of pain and its strong connection with the sense of touch.
| Type: | Article |
|---|---|
| Title: | A Simple fMRI Compatible Robotic Stimulator to Study the Neural Mechanisms of Touch and Pain |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s10439-016-1549-y |
| Publisher version: | http://dx.doi.org/10.1007/s10439-016-1549-y |
| Language: | English |
| Additional information: | Copyright © The Author(s) 2016. Published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0)(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Keywords: | Mechatronics, Nervous system, Nociception |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1495853 |
Archive Staff Only
 |
View Item |
