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Optical coherence tomography angiography: a non-invasive tool to image end-arterial system

Agrawal, R; Xin, W; Keane, PA; Chhablani, J; Agarwal, A; (2016) Optical coherence tomography angiography: a non-invasive tool to image end-arterial system. Expert Review of Medical Devices , 13 (6) pp. 519-521. 10.1080/17434440.2016.1186540. Green open access

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Abstract

Optical coherence tomography angiography (OCTA) is a relatively novel technology for in vivo imaging of vascular network. It uses moving erythrocytes as contrasting mechanism and avoids the use of intravenous dyes. A depth-resolved 3-dimensional image set can be generated within seconds using the technique of OCTA. Therefore, it possesses a great potential for widespread application in ophthalmic angiography. Herein we discuss the most common technologies behind OCTA and the scope of future technical improvement. We provide a perspective on advantages and disadvantages of OCTA over conventional fluorescein angiography and indocyanine green angiography. Lastly, current literature on the clinical application of OCTA in common ocular diseases including neovascular age-related macular degeneration, diabetic retinopathy, retinal artery and vein occlusion, and glaucoma are reviewed.

Type: Article
Title: Optical coherence tomography angiography: a non-invasive tool to image end-arterial system
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/17434440.2016.1186540
Publisher version: http://dx.doi.org/10.1080/17434440.2016.1186540
Language: English
Additional information: Copyright © 2016 Informa UK Limited, trading as Taylor & Francis Group. This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Medical Devices on 25 May 2016, available online: http://www.tandfonline.com/10.1080/17434440.2016.1186540.
Keywords: Optical coherence tomography angiography, amplitude decorrelation, optical microangiography, age-related macular degeneration, diabetic retinopathy, retinal artery occlusion, retinal vein occlusion, glaucoma
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/1494714
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