Patel, S;
Penny, CJ;
Rahman, T;
(2016)
Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed.
Trends in Biochemical Sciences
, 41
(6)
pp. 475-477.
10.1016/j.tibs.2016.04.007.
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Abstract
Two-pore channels (TPCs) are intracellular Ca(2+)-permeable ion channels that are expressed on acidic Ca(2+) stores. They are co-regulated by voltage and Ca(2+) in plant vacuoles and by the second messenger NAADP in animal endo-lysosomes. Two new studies of plant TPC structures reveal essential features of their architecture and provide mechanistic insight into their workings.
Type: | Article |
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Title: | Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.tibs.2016.04.007 |
Publisher version: | http://dx.doi.org/10.1016/j.tibs.2016.04.007 |
Language: | English |
Additional information: | © 2016 The Authors. Published by Elsevier Inc. under Creative Commons Attribution (CC BY 4.0) |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
URI: | https://discovery.ucl.ac.uk/id/eprint/1494612 |
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