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Pharmacomechanical Thrombolysis in the Management of Paget-Schroetter Syndrome

Papantoniou, E; Morgan-Rowe, L; Johnston, E; Brennand, D; Raja, J; Hague, J; (2013) Pharmacomechanical Thrombolysis in the Management of Paget-Schroetter Syndrome. Case Reports in Radiology , 2013 , Article 214804. 10.1155/2013/214804. Green open access

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Abstract

Paget-Schroetter syndrome (PSS) is a rare form of thoracic outlet syndrome caused by axillosubclavian vein thrombosis which typically presents in healthy young adults. Prompt therapy, traditionally by means of catheter-directed thrombolysis (CDT) prior to definitive surgery, can prevent the subsequent onset of postthrombotic syndrome (PTS) and considerable disability. As CDT is associated with major haemorrhage and high overall treatment cost, pharmacomechanical thrombectomy (PMT) seems to be an attractive alternative which combines pharmacological thrombolysis with mechanical clot disruption. The Trellis-8 peripheral infusion catheter is an example of such a treatment which provides topical thrombolysis in an isolated zone. We describe the use of the Trellis-8 PMT system in the successful management of three patients with PSS.

Type: Article
Title: Pharmacomechanical Thrombolysis in the Management of Paget-Schroetter Syndrome
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1155/2013/214804
Publisher version: http://dx.doi.org/10.1155/2013/214804
Language: English
Additional information: Copyright © 2013 Elli Papantoniou et al. This is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1486265
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