UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy

Eades, CP; Herbert, SA; Edwards, SG; Waters, LJ; Peake, T; Miller, RF; Jungmann, E; (2016) High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy. AIDS , 30 (1) pp. 153-156. 10.1097/QAD.0000000000000942. Green open access

[img]
Preview
Text
Miller_High_incidence_of_lymphoma_among_a_UK_cohort_of_adolescents_with_vertically_EADES_13092015_REVISEDfully1.pdf - Accepted version

Download (546kB) | Preview

Abstract

Among an inner London UK cohort of 147 adolescents transitioning from paediatric into adult care between 2007 and 2015, a new diagnosis of lymphoma was made in five patients; incidence rate = 0.425/100 person-years (95% confidence interval = 0.424–0.426). Previously described risk factors, including low nadir CD4+ cell count and ongoing HIV-1 viraemia, appeared to be important. These data suggest that careful surveillance and a low threshold for investigating relevant symptoms continue to be essential for such patients.

Type: Article
Title: High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/QAD.0000000000000942
Publisher version: http://dx.doi.org/10.1097/QAD.0000000000000942
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: science & technology, life sciences & biomedicine, immunology, infectious diseases, virology, non-Hodgkin-lymphoma, Epstein-Barr-virus, immunodeficiency syndrome, immune activation, risk-factors, children, infants, viremia, malignancies, association
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/1483881
Downloads since deposit
39Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item