Eades, CP;
Herbert, SA;
Edwards, SG;
Waters, LJ;
Peake, T;
Miller, RF;
Jungmann, E;
(2016)
High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy.
AIDS
, 30
(1)
pp. 153-156.
10.1097/QAD.0000000000000942.
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Abstract
Among an inner London UK cohort of 147 adolescents transitioning from paediatric into adult care between 2007 and 2015, a new diagnosis of lymphoma was made in five patients; incidence rate = 0.425/100 person-years (95% confidence interval = 0.424–0.426). Previously described risk factors, including low nadir CD4+ cell count and ongoing HIV-1 viraemia, appeared to be important. These data suggest that careful surveillance and a low threshold for investigating relevant symptoms continue to be essential for such patients.
| Type: | Article |
|---|---|
| Title: | High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/QAD.0000000000000942 |
| Publisher version: | http://dx.doi.org/10.1097/QAD.0000000000000942 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | science & technology, life sciences & biomedicine, immunology, infectious diseases, virology, non-Hodgkin-lymphoma, Epstein-Barr-virus, immunodeficiency syndrome, immune activation, risk-factors, children, infants, viremia, malignancies, association |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1483881 |
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