Wenz, F;
Sedlmayer, F;
Herskind, C;
Welzel, G;
Sperk, E;
Neumaier, C;
Gauter-Fleckenstein, B;
... Sütterlin, M; + view all
(2015)
Accelerated Partial Breast Irradiation in Clinical Practice.
Breast Care
, 10
(4)
pp. 247-252.
10.1159/000437194.
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Abstract
Accelerated partial breast irradiation (APBI) has been under clinical investigation for more than 15 years. There are several technical approaches that are clinically established, e.g. brachytherapy, intraoperative radiotherapy (IORT), or external-beam radiotherapy. The understanding of the underlying biology, optimal technical procedures, patient selection criteria, and imaging changes during follow-up has increased enormously. After completion of several phase III trials using brachytherapy or IORT, APBI is currently increasingly used either in phase IV studies, registries, or in selected patients outside of clinical studies. Consensus statements about suitable patients are available from several international and national societies like ASTRO, ESTRO, and DEGRO. One may expect that 15-25% of patients undergoing breast-conserving surgery may qualify for APBI, i.e. patients with small invasive ductal breast cancer without clinical lymph node involvement.
| Type: | Article |
|---|---|
| Title: | Accelerated Partial Breast Irradiation in Clinical Practice |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1159/000437194 |
| Publisher version: | http://dx.doi.org/10.1159/000437194 |
| Language: | English |
| Additional information: | This is the peer-reviewed but unedited manuscript version of the following article: Wenz, F; Sedlmayer, F; Herskind, C; Welzel, G; Sperk, E; Neumaier, C; Gauter-Fleckenstein, B; (2015) Accelerated Partial Breast Irradiation in Clinical Practice. Breast Care, 10 (4) pp. 247-252 (DOI: 10.1159/000437194). The final, published version is available at http://www.karger.com/?doi=10.1159/000437194. |
| Keywords: | Breast cancer, Intraoperative radiotherapy, Partial breast irradiation, Radiotherapy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1483818 |
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