UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Accelerated Partial Breast Irradiation in Clinical Practice

Wenz, F; Sedlmayer, F; Herskind, C; Welzel, G; Sperk, E; Neumaier, C; Gauter-Fleckenstein, B; ... Sütterlin, M; + view all (2015) Accelerated Partial Breast Irradiation in Clinical Practice. Breast Care , 10 (4) pp. 247-252. 10.1159/000437194. Green open access

[thumbnail of Vaidya_apbi-breast care-2015-final ACCEPTED.pdf]
Preview
Text
Vaidya_apbi-breast care-2015-final ACCEPTED.pdf

Download (469kB) | Preview

Abstract

Accelerated partial breast irradiation (APBI) has been under clinical investigation for more than 15 years. There are several technical approaches that are clinically established, e.g. brachytherapy, intraoperative radiotherapy (IORT), or external-beam radiotherapy. The understanding of the underlying biology, optimal technical procedures, patient selection criteria, and imaging changes during follow-up has increased enormously. After completion of several phase III trials using brachytherapy or IORT, APBI is currently increasingly used either in phase IV studies, registries, or in selected patients outside of clinical studies. Consensus statements about suitable patients are available from several international and national societies like ASTRO, ESTRO, and DEGRO. One may expect that 15-25% of patients undergoing breast-conserving surgery may qualify for APBI, i.e. patients with small invasive ductal breast cancer without clinical lymph node involvement.

Type: Article
Title: Accelerated Partial Breast Irradiation in Clinical Practice
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000437194
Publisher version: http://dx.doi.org/10.1159/000437194
Language: English
Additional information: This is the peer-reviewed but unedited manuscript version of the following article: Wenz, F; Sedlmayer, F; Herskind, C; Welzel, G; Sperk, E; Neumaier, C; Gauter-Fleckenstein, B; (2015) Accelerated Partial Breast Irradiation in Clinical Practice. Breast Care, 10 (4) pp. 247-252 (DOI: 10.1159/000437194). The final, published version is available at http://www.karger.com/?doi=10.1159/000437194.
Keywords: Breast cancer, Intraoperative radiotherapy, Partial breast irradiation, Radiotherapy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/1483818
Downloads since deposit
71Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item