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Women's views on autologous cell-based therapy for post-obstetric incontinence

Wright, B; Emmanuel, A; Athanasakos, E; Parmar, N; Parker, G; Green, B; Tailby, E; ... Day, R; + view all (2016) Women's views on autologous cell-based therapy for post-obstetric incontinence. Regenerative Medicine , 11 (2) pp. 169-180. 10.2217/rme.15.88. Green open access

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Abstract

AIM: Fecal and urinary incontinence are devastating consequences of obstetric-related perineal injury. The aim of the present study is to determine acceptability to parous women of autologous cell-based therapy for fecal and urinary incontinence that arises due to pelvic diaphragm tearing during vaginal childbirth. MATERIALS & METHODS: A multiple choice questionnaire survey was offered to 76 parous women at the Maternity Unit, University College Hospital, London, UK. Seventy completed questionnaires - response rate: 92%. RESULTS: In total, 84% of women indicated a willingness to accept autologous cell-based therapy for obstetric injury-induced incontinence rather than surgery. CONCLUSION: These observational data provide an indication of likely acceptance of autologous cell-based therapies for birth injury incontinence and will help with designing new therapeutic approaches.

Type: Article
Title: Women's views on autologous cell-based therapy for post-obstetric incontinence
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.2217/rme.15.88
Publisher version: http://dx.doi.org/10.2217/rme.15.88
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 License
Keywords: anal sphincter, autologous stem cell therapy, fecal incontinence, obstetric injury, patient preference, urinary incontinence
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1483289
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