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Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves

Colli, A; Ducci, A; Burriesci, G; (2016) Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves. New England Journal of Medicine , 374 (16) pp. 1590-1592. 10.1056/NEJMc1600179. Green open access

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Abstract

To the Editor: Makkar et al. (Nov. 19 issue)(1) report possible subclinical leaflet thrombosis in up to 40% of patients involved in a clinical trial of transcatheter aortic-valve replacement (TAVR). In contrast, we found a relatively low incidence (7%) of possible subclinical valve leaflet thrombosis among patients in our series in which 255 patients underwent TAVR with the use of a CoreValve prosthesis. A retrospective review of our series (unpublished data) showed that in 104 patients, cardiac computed tomography (CT) at a median of 7 days after implantation (range, 3 to 87) (in 51 patients), transesophageal echocardiography at a median . . .

Type: Article
Title: Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1056/NEJMc1600179
Publisher version: http://dx.doi.org/10.1056/NEJMc1600179
Language: English
Additional information: Copyright © 2016 Massachusetts Medical Society. All rights reserved.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/1482237
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