Wu, S;
Li, N;
Xia, F;
Sidlauskas, K;
Lin, X;
Qian, Y;
Gao, W;
(2014)
Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg Syndrome): case report and literature review.
BMC Neurology
, 14
, Article 231. 10.1186/s12883-014-0231-y.
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Abstract
Background: Dorsolateral medullary infarction (Wallenberg Syndrome) is rare in clinical practice; however, the subsequent corneal lesions are more uncommon. To our knowledge, only one such case was previously reported. We report a similar case with successful treatment and recovery, and analyse both cases to address the clinical features and outcomes of such syndrome. / Case presentation: A 43-year-old male presented with neurotrophic keratopathy one month after sustaining dorsolateral medullary infarction. The patient underwent amniotic membrane transplantation twice. Two-year follow-up observation revealed changes in nerve fibers and epithelial cells of corneal by laser confocal microscopy. / Conclusion: By studying both cases, we confirm that neurotrophic keratopathy could be as a delayed-onset complication of Wallenberg syndrome. The recognition that neurotrophic keratopathy can follow dorsolateral medullary infarction could prevent the clinical misdiagnosis.
| Type: | Article |
|---|---|
| Title: | Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg Syndrome): case report and literature review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/s12883-014-0231-y |
| Publisher version: | http://dx.doi.org/10.1186/s12883-014-0231-y |
| Language: | English |
| Additional information: | Copyright © Wu et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Keywords: | Dorsolateral medullary infarction, Neurotrophic keratopathy, Wallenberg syndrome |
| UCL classification: | UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1482092 |
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