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Radiologic Improvement After Early Medical Intervention in Localised Facial Morphea

Khan, MA; Shaw, L; Eleftheriou, D; Prabhakar, P; Chong, WK; Glover, M; (2016) Radiologic Improvement After Early Medical Intervention in Localised Facial Morphea. Pediatric Dermatology , 33 (2) e95-e98. 10.1111/pde.12799. Green open access

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Abstract

We report the case of a young girl who presented with hemiparesis, seizures, and subtle features consistent with a linear form of facial morphea (en coup de sabre). She was treated with pulsed parenteral steroids and oral steroids and started on methotrexate. Magnetic resonance imaging results and neurologic problems improved after 6 months. Switching off inflammation early in the course of disease seemed to reverse some of the central nervous system changes. Assessment of children with unexplained hemiparesis and seizures should include careful examination of the face and scalp, looking for subtle signs of skin change and asymmetry. This is one of the few reported cases of neuroradiologic improvement after immunosuppressive treatment in a child with en coup de sabre.

Type: Article
Title: Radiologic Improvement After Early Medical Intervention in Localised Facial Morphea
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/pde.12799
Publisher version: http://dx.doi.org/10.1111/pde.12799
Language: English
Additional information: This is the peer reviewed version of the following Khan, MA; Shaw, L; Eleftheriou, D; Prabhakar, P; Chong, WK; Glover, M; (2016) Radiologic Improvement After Early Medical Intervention in Localised Facial Morphea. Pediatric Dermatology , 33 (2) e95-e98. which has been published in final form at http://dx.doi.org/10.1111/pde.12799 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1481115
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