Frodsham, G;
Pankhurst, QA;
(2015)
Biomedical applications of high gradient magnetic separation: progress towards therapeutic haeomofiltration.
Biomedical Engineering-biomedizinische Technik
, 60
(5)
pp. 393-404.
10.1515/bmt-2015-0056.
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Abstract
High gradient magnetic separation is a well-established technology in the mineral processing industry, and has been used for decades in the bioprocessing industry. Less well known is the increasing role that high gradient magnetic separation is playing in biomedical applications, for both diagnostic and therapeutic purposes. We review here the state of the art in this emerging field, with a focus on therapeutic haemofiltration, the key enabling technologies relating to the functionalisation of magnetic nanoparticles with target-specific binding agents, and the development of extra-corporeal circuits to enable the in situ filtering of human blood.
| Type: | Article |
|---|---|
| Title: | Biomedical applications of high gradient magnetic separation: progress towards therapeutic haeomofiltration |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1515/bmt-2015-0056 |
| Publisher version: | https://doi.org/10.1515/bmt-2015-0056 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | extra-corporeal loops; functionalised carriers; magnetic separation |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1479442 |
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