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Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy

Madhusudhan, S; Keane, PA; Denniston, AK; (2016) Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy. Journal of Ophthalmic Inflammation and Infection , 6 , Article 9. 10.1186/s12348-016-0073-4. Green open access

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Abstract

A challenge in the management of 'white dot syndromes' is the lack of sensitive objective measures of disease activity. Retinal thickness maps from spectral domain optical coherence tomography (SD-OCT) inform treatment decisions in other retinal conditions such as age-related macular degeneration and diabetic maculopathy. In this report, we demonstrate their value in providing quantitative monitoring of a patient with punctate inner choroidopathy (PIC). Retinal thickness maps referenced against a baseline scan reliably detected focal areas of increased macular volume in active PIC lesions during symptomatic episodes, highlighting these as 'hot spots' that could be quantified, providing an objective basis for treatment decisions.

Type: Article
Title: Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s12348-016-0073-4
Publisher version: http://dx.doi.org/10.1186/s12348-016-0073-4
Language: English
Additional information: Copyright © Madhusudhan et al. 2016. This is an Open Access article published under the Creative Commons Attribution 4.0 International Licence (https://creativecommons.org/licenses/by/4.0/).
Keywords: Macular grid, Punctate inner choroidopathy, Retinal thickness map, SD-OCT, White dot syndromes
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/1477984
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