Tariq, M;
Kleinnijenhuis, M;
van Cappellen van Walsum, A-M;
Zhang, H;
(2015)
Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex.
In:
Proceedings of Organization for Human Brain Mapping (OHBM), 21st Annual Meeting.
OHBM: Honolulu, Hawaii.
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Abstract
This work validates the estimation of neurite dispersion anisotropy in the brain, using Bingham-NODDI [1], an extension of the diffusion MRI technique called NODDI [2]. The original NODDI provides indices of neurite (axons and dendrites) morphology that are sensitive and specific to microstructural changes [3-7]. Bingham-NODDI additionally allows the estimation of neurite dispersion anisotropy, which can enhance the accuracy of tractography algorithms [8]. The in vivo feasibility of Bingham-NODDI has been evaluated in [1]. The present study validates its indices using high-resolution ex vivo imaging data of the human primary visual cortex (V1), a well characterised region of the neocortex known to include fibres that fan or bend into the cortical layers.
Type: | Proceedings paper |
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Title: | Validation of NODDI estimation of dispersion anisotropy in V1 of the human neocortex |
Event: | Organization for Human Brain Mapping (OHBM), 21st Annual Meeting |
Location: | Honolulu, Hawaii |
Dates: | 14 June 2015 - 18 June 2015 |
Open access status: | An open access version is available from UCL Discovery |
Language: | English |
Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science |
URI: | https://discovery.ucl.ac.uk/id/eprint/1474345 |




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