Yang, Z;
Rannala, B;
(2013)
Molecular clock dating.
In: Losos, JB, (ed.)
The Princeton Guide to Evolution.
(pp. 67-74).
Princeton University Press: Princeton, NJ, USA.
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Abstract
This chapter reviews the history of the molecular clock, its impact on molecular evolution, and the controversies surrounding mechanisms of evolutionary rate variation and the application of the clock to date species divergences. We review current molecular clock dating methods, including maximum likelihood and Bayesian methods, with an emphasis on relaxing the clock and on incorporating uncertainties into fossil calibrations.
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