Yang, Z;
dos reis, M;
Donoghue, P;
(2015)
Bayesian molecular clock dating of species divergences in the genomics era.
Nature Reviews: Genetics
10.1038/nrg.2015.8.
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Abstract
It has been five decades since the proposal of the molecular clock hypothesis, which states that the rate of evolution at the molecular level is constant through time and among species. This hypothesis has become a powerful tool in evolutionary biology, making it possible to use molecular sequences to estimate the geological ages of species divergence events. With recent advances in Bayesian clock dating methodology and the explosive accumulation of genetic sequence data, molecular clock dating has found widespread applications, from tracking virus pandemics, to studying the macroevolutionary process of speciation and extinction, to estimating a timescale for Life on Earth.
| Type: | Article |
|---|---|
| Title: | Bayesian molecular clock dating of species divergences in the genomics era |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/nrg.2015.8 |
| Publisher version: | http://dx.doi.org/10.1038/nrg.2015.8 |
| Language: | English |
| Additional information: | © 2015 Macmillan Publishers Limited. All rights reserved |
| Keywords: | molecular clock, Bayesian inference, MCMC |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1473649 |
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