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Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies.

Prost, A; Binik, A; Abubakar, I; Roy, A; De Allegri, M; Mouchoux, C; Dreischulte, T; ... Osrin, D; + view all (2015) Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials , 16 , Article 351. 10.1186/s13063-015-0837-4. Green open access

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Abstract

Three arguments are usually invoked in favour of stepped wedge cluster randomised controlled trials: the logistic convenience of implementing an intervention in phases, the ethical benefit of providing the intervention to all clusters, and the potential to enhance the social acceptability of cluster randomised controlled trials. Are these alleged benefits real? We explored the logistic, ethical, and political dimensions of stepped wedge trials using case studies of six recent evaluations.

Type: Article
Title: Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s13063-015-0837-4
Publisher version: http://dx.doi.org/10.1186/s13063-015-0837-4
Additional information: © 2015 Prost et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
URI: https://discovery.ucl.ac.uk/id/eprint/1472866
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