Cain, DJ;
Del Arroyo, AG;
Ackland, GL;
(2014)
Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine.
Intensive Care Medicine Experimental
, 2
(1)
, Article 6. 10.1186/2197-425X-2-6.
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Abstract
The design of clinical immunology studies in sepsis presents several fundamental challenges to improving the translational understanding of pathologic mechanisms. We undertook a systematic review of bed-to-benchside studies to test the hypothesis that variable clinical design methodologies used to investigate immunologic function in sepsis contribute to apparently conflicting laboratory data, and identify potential alternatives that overcome various obstacles to improve experimental design.
| Type: | Article |
|---|---|
| Title: | Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/2197-425X-2-6 |
| Publisher version: | http://dx.doi.org/10.1186/2197-425X-2-6 |
| Language: | English |
| Additional information: | © 2014 Cain et al.; licensee Springer. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1472665 |
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