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Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers

Das, RK; Hindocha, C; Freeman, TP; Lazzarino, AI; Curran, HV; Kamboj, SK; (2015) Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers. Psychopharmacology , 232 (18) pp. 3363-3374. 10.1007/s00213-015-3990-2. Green open access

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Abstract

Preclinical reconsolidation research offers the first realistic opportunity to pharmacologically weaken the maladaptive memory structures that support relapse in drug addicts. N-methyl D-aspartate receptor (NMDAR) antagonism is a highly effective means of blocking drug memory reconsolidation. However, no research using this approach exists in human addicts.

Type: Article
Title: Assessing the translational feasibility of pharmacological drug memory reconsolidation blockade with memantine in quitting smokers
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00213-015-3990-2
Publisher version: http://dx.doi.org/10.1007/s00213-015-3990-2
Language: English
Additional information: © The Author(s) 2015. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/1472498
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