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The Clinical Utility of the Four Mountains Test in the Early Diagnosis of Alzhiemer's Disease: A Measure of Allocentric Memory Ability

Gore, LM; (2015) The Clinical Utility of the Four Mountains Test in the Early Diagnosis of Alzhiemer's Disease: A Measure of Allocentric Memory Ability. Doctoral thesis , University College London. Green open access

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Abstract

This thesis examines early diagnosis of dementia by understanding the impact Mild Cognitive Impairment has on quality of life (QoL) and the clinical utility of a newly developed instrument in aiding early diagnosis of AD by differentiating it from other forms of dementia. This thesis formed part of a wider PHD project that is still being completed. Part 1 is a literature review investigating the impact being diagnosed with Mild Cognitive Impairment (MCI) has on Quality of Life (QoL) in comparison to cognitively healthy controls and people with dementia. A total of 15 studies were examined. Overall, the evidence was inconsistent and methodological quality of the included research papers was weak. The review highlighted the need for further good quality research investigating the impact of MCI on QoL. Part 2 is an empirical paper that reports the findings of a study examining the clinical utility of the Four Mountains Test (4MT), a measurement of hippocampal dependent allocentric memory processing, in aiding early and differential diagnosis of AD. A total of 35 participants with differing types of early dementia from a memory service completed the 4MT alongside neuropsychological measures of memory, language, visuospatial, fluency, attention, executive function and premordid functioning. No significant results were found. Study implications and limitations are discussed with ideas for future research. Part 3 is a critical appraisal that provides reflections on the process of conducting the thesis. It discusses relevance of non-significant findings and potential of computer based tests such as the 4MT as well as the dilemmas encountered, methodological limitations and wider clinical implications of carrying out research with people with dementia.

Type: Thesis (Doctoral)
Title: The Clinical Utility of the Four Mountains Test in the Early Diagnosis of Alzhiemer's Disease: A Measure of Allocentric Memory Ability
Event: University College London
Open access status: An open access version is available from UCL Discovery
Language: English
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1472012
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