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Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches.

Copas, AJ; Lewis, JJ; Thompson, JA; Davey, C; Baio, G; Hargreaves, JR; (2015) Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials , 16 , Article 352. 10.1186/s13063-015-0842-7. Green open access

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Abstract

There is limited guidance on the design of stepped wedge cluster randomised trials. Current methodological literature focuses mainly on trials with cross-sectional data collection at discrete times, yet many recent stepped wedge trials do not follow this design. In this article, we present a typology to characterise the full range of stepped wedge designs, and offer guidance on several other design aspects.

Type: Article
Title: Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s13063-015-0842-7
Publisher version: http://dx.doi.org/10.1186/s13063-015-0842-7
Additional information: © 2015 Copas et al. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Statistical Science
URI: https://discovery.ucl.ac.uk/id/eprint/1471763
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