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Endothelial Repair in Childhood Arterial Ischaemic Stroke with Cerebral Arteriopathy

Eleftheriou, D; Ganesan, V; Hong, Y; Klein, NJ; Brogan, PA; (2015) Endothelial Repair in Childhood Arterial Ischaemic Stroke with Cerebral Arteriopathy. Cerebrovascular Diseases EXTRA , 5 (2) pp. 68-74. 10.1159/000381963. Green open access

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Abstract

We have previously shown that recurrent arterial ischaemic stroke (AIS) in children with cerebral arteriopathy is associated with increased circulating endothelial cells and endothelial microparticles, consistent with ongoing endothelial injury. To date, however, little is known about endothelial repair responses in childhood AIS. We examined the relationship between the number and function of circulating endothelial progenitor cells (EPC), the levels of brain-derived neurotrophic factor (BDNF) and AIS recurrence.

Type: Article
Title: Endothelial Repair in Childhood Arterial Ischaemic Stroke with Cerebral Arteriopathy
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000381963
Publisher version: http://dx.doi.org/10.1159/000381963
Language: English
Additional information: Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Keywords: Children, Endothelial progenitor cells, Repair, Stroke
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1471646
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