Pallares, RM;
Kong, SL;
Hui Ru, T;
Thanh, NTK;
Lu, Y;
Su, X;
(2015)
A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification.
Chemical Communications
, 51
(77)
pp. 14524-14527.
10.1039/C5CC05331E.
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Abstract
A plasmonic nanosensor (using gold nanorods) with inverse sensitivity is presented for circulating cell-free DNA quantification. The inverse sensitivity (i.e. the lower the analyte concentration, the higher the response intensity) is achieved by the unusual DNA concentration-dependent gold nanorod aggregation. This assay method can adjust the dynamic range by controlling the concentration of nanoparticles in solution. Graphical abstract: A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification
| Type: | Article |
|---|---|
| Title: | A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/C5CC05331E |
| Publisher version: | http://dx.doi.org/10.1039/C5CC05331E |
| Language: | English |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Physics and Astronomy |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1471377 |
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