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Exogenous contrast agents for thermoacoustic imaging: an investigation into the underlying sources of contrast.

Ogunlade, O; Beard, P; (2015) Exogenous contrast agents for thermoacoustic imaging: an investigation into the underlying sources of contrast. Med Phys , 42 (1) pp. 170-180. 10.1118/1.4903277. Green open access

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Abstract

Thermoacoustic imaging at microwave excitation frequencies is limited by the low differential contrast exhibited by high water content tissues. To overcome this, exogenous thermoacoustic contrast agents based on gadolinium compounds, iron oxide, and single wall carbon nanotubes have previously been suggested and investigated. However, these previous studies did not fully characterize the electric, magnetic, and thermodynamic properties of these agents thus precluding identification of the underlying sources of contrast. To address this, measurements of the complex permittivity, complex permeability, DC conductivity, and Grüneisen parameter have been made. These measurements allowed the origins of the contrast provided by each substance to be identified.

Type: Article
Title: Exogenous contrast agents for thermoacoustic imaging: an investigation into the underlying sources of contrast.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1118/1.4903277
Publisher version: http://dx.doi.org/10.1118/1.4903277
Language: English
Additional information: © 2015 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.
Keywords: Acoustics, Contrast Media, Ferric Compounds, Gadolinium, Microwaves, Molecular Imaging, Nanotubes, Carbon, Permeability, Sodium Chloride, Sucrose
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1471315
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