Constantinou, L;
Bayford, R;
Demosthenous, A;
(2015)
A Wideband Low-Distortion CMOS Current Driver for Tissue Impedance Analysis.
A Wideband Low-Distortion CMOS Current Driver for Tissue Impedance Analysis
, 62
(2)
pp. 154-158.
10.1109/TCSII.2014.2387632.
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Abstract
Abstract—Bioimpedance measurements are performed in a variety of medical applications including cancer detection in tissue. Such applications require wideband (typically 1 MHz) accurate ac current drivers with high output impedance and low distortion. This paper presents an integrated current driver that fulfills these requirements. The circuit uses negative feedback to accurately set the output current amplitude into the load. It was fabricated in a 0.35-μm complementary metal–oxide–semiconductor (CMOS) process technology, occupies a core area of 0.4 mm2, and operates from ±2.5-V power supplies. For a maximum output current of 1 mAp-p, the measured total harmonic distortion is below 0.1%, and the variability of the output current with respect to the load is below 0.5% up to 800 kHz increasing to 0.86% at 1 MHz. The current driver was tested for the detection of cancer sites from postoperative human colon specimens. The circuit is intended for use in active electrode applications.
| Type: | Article |
|---|---|
| Title: | A Wideband Low-Distortion CMOS Current Driver for Tissue Impedance Analysis |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/TCSII.2014.2387632 |
| Publisher version: | http://dx.doi.org/10.1109/TCSII.2014.2387632 |
| Language: | English |
| Additional information: | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Active electrodes, bioimpedance, cancer detection, integrated current driver, low distortion, wideband |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1470190 |
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