Head, MG; Fitchett, JR; Cassell, JA; Atun, R; (2015) Investments in sexually transmitted infection research 1997-2013: a systematic analysis of funding awarded to UK institutions. Journal of Global Health , 5 (2) , Article 020405. 10.7189/jogh.05.020405.

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Abstract

BACKGROUND: We report the first study that analyses public and philanthropic investments awarded to UK institutions for research related to sexually transmitted infections (STIs). METHODS: We systematically searched award data from the major funders for information on all infectious disease research funding awarded 1997–2013. The STI-related projects were identified and categorised by pathogen, disease and type of science along the research pipeline from preclinical to translational research. FINDINGS: We identified 7393 infection-related awards with total investment of £3.5 billion. Of these, 1238 awards (16.7%) covering funding of £719.1 million (20.5%) were for STI research. HIV as an STI received £465 million across 719 studies; non-HIV STIs received £139 million across 378 studies. The Medical Research Council provided greatest investment (£193 million for HIV, £45 million for non-HIV STIs). Preclinical awards totalled £233 million (37.1%), whilst translational research received £286 million (39.7%). Substantial proportions of HIV investment addressed global health research (£265 million), vaccinology (£110 million) and therapeutics (£202 million). For other STIs, investments focused on diagnostics (£45 million) and global health (£27 million). Human Papilloma Virus research received £58 million and chlamydia £24 million. Funding for non-HIV STIs has declined in the three most recent years of this dataset. CONCLUSIONS: The investment for HIV research awarded to UK institutions correlates with the high global burden, but other STIs are relatively neglected, including gonorrhoea and syphilis. Future STI funding should be better aligned with burden while addressing the emerging risk of antimicrobial resistance in Neisseria gonorrhoeae and outbreaks of other pathogens.

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