Bazin-Lopez, N;
Valdivia, LE;
Wilson, SW;
Gestri, G;
(2015)
Watching eyes take shape.
Current Opinion in Genetics & Development
, 32C
73 - 79.
10.1016/j.gde.2015.02.004.
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Abstract
Vertebrate eye formation is a multistep process requiring coordinated inductive interactions between neural and non-neural ectoderm and underlying mesendoderm. The induction and shaping of the eyes involves an elaborate cellular choreography characterized by precise changes in cell shape coupled with complex cellular and epithelial movements. Consequently, the forming eye is an excellent model to study the cellular mechanisms underlying complex tissue morphogenesis. Using examples largely drawn from recent studies of optic vesicle formation in zebrafish and in cultured embryonic stem cells, in this short review, we highlight some recent advances in our understanding of the events that shape the vertebrate eye.
| Type: | Article |
|---|---|
| Title: | Watching eyes take shape |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.gde.2015.02.004 |
| Publisher version: | http://dx.doi.org/10.1016/j.gde.2015.02.004 |
| Additional information: | © 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecom-mons.org/licenses/by/4.0/). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1467317 |
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