UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Watching eyes take shape

Bazin-Lopez, N; Valdivia, LE; Wilson, SW; Gestri, G; (2015) Watching eyes take shape. Current Opinion in Genetics & Development , 32C 73 - 79. 10.1016/j.gde.2015.02.004. Green open access

[thumbnail of Watching eyes take shape.pdf]
Preview
Text
Watching eyes take shape.pdf

Download (882kB) | Preview

Abstract

Vertebrate eye formation is a multistep process requiring coordinated inductive interactions between neural and non-neural ectoderm and underlying mesendoderm. The induction and shaping of the eyes involves an elaborate cellular choreography characterized by precise changes in cell shape coupled with complex cellular and epithelial movements. Consequently, the forming eye is an excellent model to study the cellular mechanisms underlying complex tissue morphogenesis. Using examples largely drawn from recent studies of optic vesicle formation in zebrafish and in cultured embryonic stem cells, in this short review, we highlight some recent advances in our understanding of the events that shape the vertebrate eye.

Type: Article
Title: Watching eyes take shape
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.gde.2015.02.004
Publisher version: http://dx.doi.org/10.1016/j.gde.2015.02.004
Additional information: © 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecom-mons.org/licenses/by/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/1467317
Downloads since deposit
50Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item