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Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.

Alimohammadi, M; Sherwood, JM; Karimpour, M; Agu, O; Balabani, S; Díaz-Zuccarini, V; (2015) Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models. Biomed Eng Online , 14 (1) , Article 34. 10.1186/s12938-015-0032-6. Green open access

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Abstract

The management and prognosis of aortic dissection (AD) is often challenging and the use of personalised computational models is being explored as a tool to improve clinical outcome. Including vessel wall motion in such simulations can provide more realistic and potentially accurate results, but requires significant additional computational resources, as well as expertise. With clinical translation as the final aim, trade-offs between complexity, speed and accuracy are inevitable. The present study explores whether modelling wall motion is worth the additional expense in the case of AD, by carrying out fluid-structure interaction (FSI) simulations based on a sample patient case.

Type: Article
Title: Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s12938-015-0032-6
Publisher version: http://dx.doi.org/10.1186/s12938-015-0032-6
Language: English
Additional information: © 2015 Alimohammadi et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Fluid-structure interaction; Aortic dissection; Intimal flap; FSI; AD
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/1466785
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