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Accelerated motion corrected three-dimensional abdominal MRI using total variation regularized SENSE reconstruction

Cruz, G; Atkinson, D; Buerger, C; Schaeffter, T; Prieto, C; (2016) Accelerated motion corrected three-dimensional abdominal MRI using total variation regularized SENSE reconstruction. Magnetic Resonance in Medicine , 75 (4) pp. 1484-1498. 10.1002/mrm.25708. Green open access

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Abstract

PURPOSE: Develop a nonrigid motion corrected reconstruction for highly accelerated free-breathing three-dimensional (3D) abdominal images without external sensors or additional scans. METHODS: The proposed method accelerates the acquisition by undersampling and performs motion correction directly in the reconstruction using a general matrix description of the acquisition. Data are acquired using a self-gated 3D golden radial phase encoding trajectory, enabling a two stage reconstruction to estimate and then correct motion of the same data. In the first stage total variation regularized iterative SENSE is used to reconstruct highly undersampled respiratory resolved images. A nonrigid registration of these images is performed to estimate the complex motion in the abdomen. In the second stage, the estimated motion fields are incorporated in a general matrix reconstruction, which uses total variation regularization and incorporates k-space data from multiple respiratory positions. The proposed approach was tested on nine healthy volunteers and compared against a standard gated reconstruction using measures of liver sharpness, gradient entropy, visual assessment of image sharpness and overall image quality by two experts. RESULTS: The proposed method achieves similar quality to the gated reconstruction with nonsignificant differences for liver sharpness (1.18 and 1.00, respectively), gradient entropy (1.00 and 1.00), visual score of image sharpness (2.22 and 2.44), and visual rank of image quality (3.33 and 3.39). An average reduction of the acquisition time from 102 s to 39 s could be achieved with the proposed method. CONCLUSION: In vivo results demonstrate the feasibility of the proposed method showing similar image quality to the standard gated reconstruction while using data corresponding to a significantly reduced acquisition time.

Type: Article
Title: Accelerated motion corrected three-dimensional abdominal MRI using total variation regularized SENSE reconstruction
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mrm.25708
Publisher version: http://dx.doi.org/10.1002/mrm.25708
Language: English
Additional information: Copyright © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: abdominal MRI, motion correction, nonrigid motion, total variation, undersampling
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/1466274
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