Hardy, R;
Lawlor, DA;
Kuh, D;
(2015)
A life course approach to cardiovascular aging.
Future Cardiol
, 11
(1)
101 - 113.
10.2217/fca.14.67.
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Abstract
A life course approach in epidemiology investigates the biological, behavioral and social pathways that link physical and social exposures and experiences during gestation, childhood, adolescence and adult life, and across generations, to later-life health and disease risk. We illustrate how a life course approach has been applied to cardiovascular disease, highlighting the evidence in support of the early origins of disease risk. We summarize how trajectories of cardiometabolic risk factors change over the life course and suggest that understanding underlying 'normal' or 'healthy' trajectories and the characteristics that drive deviations from such trajectories offer the potential for early prevention and for identifying means of preventing future disease.
| Type: | Article |
|---|---|
| Title: | A life course approach to cardiovascular aging. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.2217/fca.14.67 |
| Publisher version: | http://dx.doi.org/DOI 10.2217/fca.14.67 |
| Language: | English |
| Additional information: | © Rebecca Hardy, Diana Kuh, Debbie Lawler This article is distributed under the terms of the Creative Commons Attribution License 3.0 which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. To view a copy of the license, visit http://creativecommons.org/ licenses/by/3.0/ |
| Keywords: | adiposity, birth weight, blood pressure, cardiovascular disease, cohort studies, glucose, life course, lipids, longitudinal modeling, social inequalities |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Social Research Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1465740 |
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