UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research.

Kirkbride, JB; (2014) The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research. Soc Psychiatry Psychiatr Epidemiol , 49 (10) 1531 - 1534. 10.1007/s00127-014-0961-6. Green open access

[thumbnail of Kirkbride, J. The emerging molecular architecture of schizophrenia .pdf]
Preview
Text
Kirkbride, J. The emerging molecular architecture of schizophrenia .pdf

Download (133kB) | Preview

Abstract

In this commentary I review the recent paper by Iyegbe et al. on "The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research". I discuss how the paper advances our knowledge of polygenic risk scores for use, amongst others, in gene-environment interaction studies and the opportunities and challenges such approaches will bring to our understanding of the epidemiology of psychotic disorders, including schizophrenia.

Type: Article
Title: The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research.
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00127-014-0961-6
Publisher version: http://dx.doi.org/10.1007/s00127-014-0961-6
Language: English
Additional information: © The Author(s) 2014 Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Keywords: Environment, Gene-Environment Interaction, Humans, Models, Statistical, Molecular Biology, Schizophrenia
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/1465182
Downloads since deposit
67Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item