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Increased percentages of regulatory T cells are associated with inflammatory and neuroendocrine responses to acute psychological stress and poorer health status in older men and women.

Ronaldson, A; Gazali, AM; Zalli, A; Kaiser, F; Thompson, SJ; Henderson, B; Steptoe, A; (2015) Increased percentages of regulatory T cells are associated with inflammatory and neuroendocrine responses to acute psychological stress and poorer health status in older men and women. Psychopharmacology , 233 (9) pp. 1661-1668. 10.1007/s00213-015-3876-3. Green open access

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Abstract

The percentage of regulatory T cells (TRegs)-a subtype of T lymphocyte that suppresses the immune response-appears to be reduced in a number of stress-related diseases. The role of the TReg in stress-disease pathways has not yet been investigated.

Type: Article
Title: Increased percentages of regulatory T cells are associated with inflammatory and neuroendocrine responses to acute psychological stress and poorer health status in older men and women.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00213-015-3876-3
Publisher version: http://dx.doi.org/10.1007/s00213-015-3876-3
Language: English
Additional information: © The Author(s) 2015. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Keywords: Regulatory T cell; Psychological stress; HPA axis Inflammatory response system; Depression
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/1464763
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