Fraser, SD;
Aitken, G;
Taal, MW;
Mindell, JS;
Moon, G;
Day, J;
O'Donoghue, D;
(2015)
Exploration of chronic kidney disease prevalence estimates using new measures of kidney function in the health survey for England.
PLoS One
, 10
(2)
, Article e0118676. 10.1371/journal.pone.0118676.
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Abstract
Chronic kidney disease (CKD) diagnosis relies on glomerular filtration rate (eGFR) estimation, traditionally using the creatinine-based Modification of Diet in Renal Disease (MDRD) equation. The Chronic Kidney Disease Epidemiology Collaboration (CKDEPI) equation performs better in estimating eGFR and predicting mortality and CKD progression risk. Cystatin C is an alternative glomerular filtration marker less influenced by muscle mass. CKD risk stratification is improved by combining creatinine eGFR with cystatin C and urinary albumin to creatinine ratio (uACR). We aimed to identify the impact of introducing CKDEPI and cystatin C on the estimated prevalence and risk stratification of CKD in England and to describe prevalence and associations of cystatin C.
| Type: | Article |
|---|---|
| Title: | Exploration of chronic kidney disease prevalence estimates using new measures of kidney function in the health survey for England |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pone.0118676 |
| Publisher version: | http://dx.doi.org/10.1371/journal.pone.0118676 |
| Language: | English |
| Additional information: | © 2015 Fraser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License [ http://creativecommons.org/licenses/by/4.0/ ], which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1464642 |
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