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Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies.

Binder, E; Natarajan, D; Cooper, J; Kronfli, R; Cananzi, M; Delalande, JM; McCann, C; ... Thapar, N; + view all (2015) Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies. PLoS One , 10 (3) , Article e0119467 . 10.1371/journal.pone.0119467. Green open access

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Abstract

Enteric neural stem cells provide hope of curative treatment for enteric neuropathies. Current protocols for their harvesting from humans focus on the generation of 'neurospheres' from cultures of dissociated gut tissue. The study aims to better understand the derivation, generation and composition of enteric neurospheres.

Type: Article
Title: Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0119467
Publisher version: http://dx.doi.org/10.1371/journal.pone.0119467
Language: English
Additional information: © 2015 Binder et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1461841
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