Guardiola, M;
Exeter, HJ;
Perret, C;
Folkersen, L;
Van't Hooft, F;
Eriksson, P;
Franco-Cereceda, A;
... Talmud, PJ; + view all
(2015)
PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk.
Circ Cardiovasc Genet
, 8
(2)
356 - 362.
10.1161/CIRCGENETICS.114.000633.
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Abstract
Observational studies report that secretory phospholipase A2 (sPLA2) activity is a marker for coronary heart disease (CHD) risk, and activity measures are thought to represent the composite activity of sPLA2-IIA, -V, and -X. The aim of this study was to use genetic variants of PLA2G10, encoding sPLA2-X, to investigate the contribution of sPLA2-X to the measure of sPLA2 activity and coronary heart disease (CHD) risk traits and outcome.
| Type: | Article |
|---|---|
| Title: | PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1161/CIRCGENETICS.114.000633 |
| Publisher version: | http://dx.doi.org/10.1161/CIRCGENETICS.114.000633 |
| Language: | English |
| Additional information: | © 2015 American Heart Association, Inc. |
| Keywords: | PLA2G10, genetic polymorphism |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1461268 |
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