Poulton, K;
Ripoll, VM;
Pericleous, C;
Meroni, PL;
Gerosa, M;
Ioannou, Y;
Rahman, A;
(2015)
Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion.
American Journal of Reproductive Immunology
, 73
(5)
pp. 390-401.
10.1111/aji.12341.
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Abstract
Some patients with antiphospholipid syndrome (APS) suffer pregnancy morbidity (PM) but not vascular thrombosis (VT), whilst others suffer VT only. Therefore, we compared the effects of IgG from VT+/PM- and VT-/PM+ subjects on human first-trimester trophoblast (HTR8) cells.
| Type: | Article |
|---|---|
| Title: | Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/aji.12341 |
| Publisher version: | http://dx/doi.org/10.1111/aji.12341 |
| Language: | English |
| Additional information: | © 2014 The Authors American Journal of Reproductive Immunology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Antiphospholipid, TLR4, obstetric, trophoblast |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1458301 |
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