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Will Incremental Hemodialysis Preserve Residual Function and Improve Patient Survival?

Davenport, A; (2015) Will Incremental Hemodialysis Preserve Residual Function and Improve Patient Survival? Semin Dial , 28 (1) pp. 16-19. 10.1111/sdi.12320. Green open access

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Abstract

The progressive loss of residual renal function in peritoneal dialysis patients is associated with increased mortality. It has been suggested that incremental dialysis may help preserve residual renal function and improve patient survival. Residual renal function depends upon both patient related and dialysis associated factors. Maintaining patients in an over-hydrated state may be associated with better preservation of residual renal function but any benefit comes with a significant risk of cardiovascular consequences. Notably, it is only observational studies that have reported an association between dialysis patient survival and residual renal function; causality has not been established for dialysis patient survival. The tenuous connections between residual renal function and outcomes and between incremental hemodialysis and residual renal function should temper our enthusiasm for interventions in this area.

Type: Article
Title: Will Incremental Hemodialysis Preserve Residual Function and Improve Patient Survival?
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/sdi.12320
Publisher version: http://dx.doi.org/10.1111/sdi.12320
Additional information: © 2014 The Authors. Seminars in Dialysis published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1457272
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