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Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study

Hamer, M; von Känel, R; Reimann, M; Malan, NT; Schutte, AE; Huisman, HW; Malan, L; (2015) Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study. Atherosclerosis , 238 (1) 52 - 54. 10.1016/j.atherosclerosis.2014.11.019. Green open access

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Abstract

Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p= 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 hr systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.

Type: Article
Title: Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.atherosclerosis.2014.11.019
Publisher version: http://dx.doi.org/10.1016/j.atherosclerosis.2014.1...
Language: English
Additional information: ©2014 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-SA license ( http://creativecommons.org/licenses/by-nc-sa/3.0/).
Keywords: Black African,Biomarkers,Cardiovascular disease,Epidemiology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/1457228
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