Swanton, C;
Beck, SA;
(2014)
Epigenetic noise fuels cancer evolution.
Cancer Cell
, 26
(6)
pp. 775-776.
10.1016/j.ccell.2014.11.003.
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Abstract
Cancer is a disease of the genome and the epigenome. Previous studies have shown that genomic changes such as mutations, copy number variation, and genomic rearrangements drive cancer evolution. In this issue of Cancer Cell, Landau and colleagues add epigenomic changes, specifically locally disordered DNA methylation, to cancer’s evolutionary trajectory.
| Type: | Article |
|---|---|
| Title: | Epigenetic noise fuels cancer evolution |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ccell.2014.11.003 |
| Publisher version: | http://dx.doi.org/10.1016/j.ccell.2014.11.003 |
| Language: | English |
| Additional information: | Copyright © 2014. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1456626 |
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