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Asthma trajectories in early childhood: identifying modifiable factors.

Panico, L; Stuart, B; Bartley, M; Kelly, Y; (2014) Asthma trajectories in early childhood: identifying modifiable factors. PLoS One , 9 (11) , Article e111922. 10.1371/journal.pone.0111922. Green open access

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[thumbnail of Supporting Information: ISAAC Core Questionnaire for Wheezing and Asthma.] Text (Supporting Information: ISAAC Core Questionnaire for Wheezing and Asthma.)
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Abstract

There are conflicting views as to whether childhood wheezing represents several discreet entities or a single but variable disease. Classification has centered on phenotypes often derived using subjective criteria, small samples, and/or with little data for young children. This is particularly problematic as asthmatic features appear to be entrenched by age 6/7. In this paper we aim to: identify longitudinal trajectories of wheeze and other atopic symptoms in early childhood; characterize the resulting trajectories by the socio-economic background of children; and identify potentially modifiable processes in infancy correlated with these trajectories.

Type: Article
Title: Asthma trajectories in early childhood: identifying modifiable factors.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0111922
Publisher version: http://dx.doi.org/10.1371/journal.pone.0111922
Language: English
Additional information: © 2014 Panico et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/1456098
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