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Obesity, Diet, Physical Activity and Health-Related Quality of Life in Endometrial Cancer Survivors: A Systematic Review

Koutoukidis, D; Knobf, MT; Lanceley, A; (2014) Obesity, Diet, Physical Activity and Health-Related Quality of Life in Endometrial Cancer Survivors: A Systematic Review. Nutrition Reviews , 73 (6) pp. 399-408. 10.1093/nutrit/nuu063. Green open access

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Abstract

Obesity, low-quality diet and inactivity are prevalent among endometrial cancer survivors. A systematic review was conducted to assess if they are associated with health-related quality of life (HRQoL). Search included electronic databases, conference abstracts, reference lists, and contacting experts. Methodological and reporting quality was evaluated with appropriate checklists. Standardised mean differences were calculated and data were synthesised narratively. Eight from the 4385 retrieved reports were included. Four of eight studies were cross-sectional, one retrospective, one prospective and two were randomised-controlled trials. Obesity was negatively associated with overall HRQoL in 4/4 studies and with physical well-being in 6/6 studies, while positively associated with fatigue in 2/4 studies. Meeting the recommendations for being physically active, eating a diet high in fruit and vegetables, and/or abstaining from smoking were positively associated with overall HRQoL in 2/2 studies, with physical well-being in 2/3 studies and with fatigue in 1/3 studies. Improvements in fatigue and physical well-being were evident after lifestyle interventions. Healthy lifestyle is positively associated with HRQoL. Trials need to test interventions promoting healthy lifestyle in this population.

Type: Article
Title: Obesity, Diet, Physical Activity and Health-Related Quality of Life in Endometrial Cancer Survivors: A Systematic Review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/nutrit/nuu063
Publisher version: http://dx.doi.org/10.1093/nutrit/nuu063
Language: English
Additional information: © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs license (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords: endometrial cancer, survivors, quality of life, obesity, healthy lifestyle, systematic review
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Womens Cancer
URI: https://discovery.ucl.ac.uk/id/eprint/1455980
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